Leptin is a hormone produced by body fat that affects the appetite control centre in the brain.

When the body loses fat the lack of Leptin stimulates the appetite. When fat accumulates the extra levels of Leptin depress our interest in food.

It was found that obese mice mice with a certain genetic mutation failed to produce Leptin. Further findings show that a persons appetite and their eating patterns may be linked to specific genes.

Only a very small change in a DNA sequence may mean the difference between slim or obese.

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